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PICO describes the four elements of a good clinical foreground question:
P = Population/Patient/Problem - How would I describe the problem or a group of patients similar to mine?
I = Intervention - What main intervention, prognostic factor or exposure am I considering?
C = Comparison - Is there an alternative to compare with the intervention?
O = Outcome - What do I hope to accomplish, measure, improve or affect?
For more information about developing a PICO question and how to do PICO research see the "Development of PICO" page in the Writing in the Health Sciences LibGuide here: https://libguides.hofstra.edu/WritingInTheHealthSciences/PICO
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